Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.
Identifieur interne : 004337 ( Main/Exploration ); précédent : 004336; suivant : 004338Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.
Auteurs : Hiromichi Yamane [Japon] ; Nobuaki Ochi ; Takayuki Tabayashi ; Lu Lu ; Tomoko Yamagishi ; Yasumasa Monobe ; Takehiro Tanaka ; Eisei Kondoh ; Nagio TakigawaSource :
- Internal medicine (Tokyo, Japan) [ 1349-7235 ] ; 2012.
Descripteurs français
- KwdFr :
- Cuisse, Facteur VIII (métabolisme), Facteur de von Willebrand (métabolisme), Femelle, Humains, Immunohistochimie, Issue fatale, Lymphangiosarcome (diagnostic), Lymphangiosarcome (immunologie), Lymphangiosarcome (sang), Lymphangiosarcome (étiologie), Lymphoedème (), Sujet âgé, Tumeurs du col de l'utérus ().
- MESH :
- diagnostic : Lymphangiosarcome.
- immunologie : Lymphangiosarcome.
- métabolisme : Facteur VIII, Facteur de von Willebrand.
- sang : Lymphangiosarcome.
- étiologie : Lymphangiosarcome.
- Cuisse, Femelle, Humains, Immunohistochimie, Issue fatale, Lymphoedème, Sujet âgé, Tumeurs du col de l'utérus.
English descriptors
- KwdEn :
- Aged, Factor VIII (metabolism), Fatal Outcome, Female, Humans, Immunohistochemistry, Lymphangiosarcoma (blood), Lymphangiosarcoma (diagnosis), Lymphangiosarcoma (etiology), Lymphangiosarcoma (immunology), Lymphedema (complications), Thigh, Uterine Cervical Neoplasms (complications), von Willebrand Factor (metabolism).
- MESH :
- chemical , metabolism : Factor VIII, von Willebrand Factor.
- blood : Lymphangiosarcoma.
- complications : Lymphedema, Uterine Cervical Neoplasms.
- diagnosis : Lymphangiosarcoma.
- etiology : Lymphangiosarcoma.
- immunology : Lymphangiosarcoma.
- Aged, Fatal Outcome, Female, Humans, Immunohistochemistry, Thigh.
Abstract
A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.
PubMed: 23154736
Affiliations:
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Le document en format XML
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<author><name sortKey="Yamagishi, Tomoko" sort="Yamagishi, Tomoko" uniqKey="Yamagishi T" first="Tomoko" last="Yamagishi">Tomoko Yamagishi</name>
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<author><name sortKey="Monobe, Yasumasa" sort="Monobe, Yasumasa" uniqKey="Monobe Y" first="Yasumasa" last="Monobe">Yasumasa Monobe</name>
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<author><name sortKey="Tanaka, Takehiro" sort="Tanaka, Takehiro" uniqKey="Tanaka T" first="Takehiro" last="Tanaka">Takehiro Tanaka</name>
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<author><name sortKey="Kondoh, Eisei" sort="Kondoh, Eisei" uniqKey="Kondoh E" first="Eisei" last="Kondoh">Eisei Kondoh</name>
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<author><name sortKey="Takigawa, Nagio" sort="Takigawa, Nagio" uniqKey="Takigawa N" first="Nagio" last="Takigawa">Nagio Takigawa</name>
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<term>Factor VIII (metabolism)</term>
<term>Fatal Outcome</term>
<term>Female</term>
<term>Humans</term>
<term>Immunohistochemistry</term>
<term>Lymphangiosarcoma (blood)</term>
<term>Lymphangiosarcoma (diagnosis)</term>
<term>Lymphangiosarcoma (etiology)</term>
<term>Lymphangiosarcoma (immunology)</term>
<term>Lymphedema (complications)</term>
<term>Thigh</term>
<term>Uterine Cervical Neoplasms (complications)</term>
<term>von Willebrand Factor (metabolism)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Cuisse</term>
<term>Facteur VIII (métabolisme)</term>
<term>Facteur de von Willebrand (métabolisme)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Immunohistochimie</term>
<term>Issue fatale</term>
<term>Lymphangiosarcome (diagnostic)</term>
<term>Lymphangiosarcome (immunologie)</term>
<term>Lymphangiosarcome (sang)</term>
<term>Lymphangiosarcome (étiologie)</term>
<term>Lymphoedème ()</term>
<term>Sujet âgé</term>
<term>Tumeurs du col de l'utérus ()</term>
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<term>von Willebrand Factor</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lymphedema</term>
<term>Uterine Cervical Neoplasms</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lymphangiosarcoma</term>
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<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Lymphangiosarcome</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphangiosarcoma</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Lymphangiosarcoma</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Facteur VIII</term>
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<term>Femelle</term>
<term>Humains</term>
<term>Immunohistochimie</term>
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<front><div type="abstract" xml:lang="en">A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.</div>
</front>
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<affiliations><list><country><li>Japon</li>
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<tree><noCountry><name sortKey="Kondoh, Eisei" sort="Kondoh, Eisei" uniqKey="Kondoh E" first="Eisei" last="Kondoh">Eisei Kondoh</name>
<name sortKey="Lu, Lu" sort="Lu, Lu" uniqKey="Lu L" first="Lu" last="Lu">Lu Lu</name>
<name sortKey="Monobe, Yasumasa" sort="Monobe, Yasumasa" uniqKey="Monobe Y" first="Yasumasa" last="Monobe">Yasumasa Monobe</name>
<name sortKey="Ochi, Nobuaki" sort="Ochi, Nobuaki" uniqKey="Ochi N" first="Nobuaki" last="Ochi">Nobuaki Ochi</name>
<name sortKey="Tabayashi, Takayuki" sort="Tabayashi, Takayuki" uniqKey="Tabayashi T" first="Takayuki" last="Tabayashi">Takayuki Tabayashi</name>
<name sortKey="Takigawa, Nagio" sort="Takigawa, Nagio" uniqKey="Takigawa N" first="Nagio" last="Takigawa">Nagio Takigawa</name>
<name sortKey="Tanaka, Takehiro" sort="Tanaka, Takehiro" uniqKey="Tanaka T" first="Takehiro" last="Tanaka">Takehiro Tanaka</name>
<name sortKey="Yamagishi, Tomoko" sort="Yamagishi, Tomoko" uniqKey="Yamagishi T" first="Tomoko" last="Yamagishi">Tomoko Yamagishi</name>
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<country name="Japon"><noRegion><name sortKey="Yamane, Hiromichi" sort="Yamane, Hiromichi" uniqKey="Yamane H" first="Hiromichi" last="Yamane">Hiromichi Yamane</name>
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